The vertical spiral belt vacuum drying mixer is a multifunctional drying equipment that integrates mixing, reaction, and drying, especially suitable for multiple industries such as food, adhesives, and lithium batteries. This device is equipped with a heating jacket, and the spindle and screw can also be equipped with heating function to further improve drying efficiency. Its main shaft adopts mechanical sealing, which can achieve high vacuum sealing and connect to a vacuum system for efficient drying. Its drying efficiency far exceeds traditional dryers of the same specifications, such as double cone rotary vacuum dryers. In order to reduce raw material loss and environmental pollution, the equipment is equipped with a dust removal device, a condensation recovery device, and a solid gas separation device at the front end of the vacuum device. In addition, the entire system can achieve PLC automation control, such as temperature, vacuum degree, and speed regulation, and is equipped with signal interfaces for remote operation, ensuring the efficiency and safety of operations.